Profile
Sarah Mistry
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About Me:
I am a Postdoctoral Researcher at the University of Nottingham. Outside of the lab I like practising yoga, growing veg in my allotment and hiking.
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I currently live in Nottingham with my husband but I have also lived in Essex (where I am from), France and Australia. I love to travel and recent trips have been to Malaysia, the US and Canada. In my spare time I also like to cook, practise yoga and pilates, grow veg in my allotment and go hiking –Β especially in the nearby Peak District.
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My work as a researcher is mainly to make fluorescent molecules for proteins at the cell surface. These proteins transmit messages from outside the cell to the inside and tell the cell which processes to start or stop. You can see the fluorescent molecules bound to their target if you excite them with a laser and then examine the cells under a very powerful microscope. These molecules can be used for many different experiments. For example, you can investigate where the proteins are in the cells and also how well new non-fluorescent molecules can bind to the proteins. This helps us to investigate how the proteins work and to develop new medicines.
This photo shows test tubes containing some fluorescent molecules that I have made.
This photo shows fluorescent molecules that I have made bound to cells (red image)
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My Typical Day:
On a typical day, I cycle to work arriving at 9am. I check my email then start working in the lab. Here I start some reactions, purify some molecules and analyse them to make sure that they are pure. At around 6pm I cycle home or go to pilates or yoga.
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My day usually starts by checking my emails in the office, then making my way to the lab where I will check my reactions that have been running overnight. I will then start new reactions and purify some compounds that I have made.
You can see a short video of a reaction that I have done here:Β Reaction clip
At lunchtime I sometimes go for a walk around the university campus with friends and have a coffee. The campus is very pretty and has a lake. There is a lot of wildlife to see such as squirrels and geese.
I will then return to the lab to check the reactions that I started in the morning, and if they are finished then I will purify the compounds and then analyse them to make sure that they are pure.
This photo shows a purification technique that I use to purify compounds called preparative layer chromatography. I use this technique, in addition to others, to separate mixtures of molecules that I have made in my reactions.
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What I'd do with the prize money:
I would use the money to buy equipment for outreach activities with local schools in Nottingham that our department has links with.
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Education:
Tabor High School, Braintree,
The Sixth Form College, Colchester,
University of Leicester,
UniversitΓ© de Nice – Sophia Antipolis,
University of Nottingham. -
Qualifications:
GCSEs – Double Science, Maths, English Lit, English Language, French, Art, Geography, IT,
A levels – Chemistry, Biology, Physics, General Studies,
BSc – Chemistry/Europe,
PhD – Pharmacy (Medicinal Chemistry). -
Work History:
Shop Assistant, Bar staff, Supermarket Online Shopper, Synthetic Organic Chemist, Admin Assistant, Postdoctoral researcher.
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Current Job:
Postdoctoral Researcher
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My Interview
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How would you describe yourself in 3 words?
Hardworking, conscientious and friendly.
What did you want to be after you left school?
A Vet
Were you ever in trouble at school?
No
Who is your favourite singer or band?
Michael Kiwanuka
What's your favourite food?
Chocolate
If you had 3 wishes for yourself what would they be? - be honest!
To travel more, to become fluent in French, to live in another country again.
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